NOX4/NADPH Oxidase 4 Antibody MBS4380143 from MyBioSource.com

Product Specs
ItemNOX4/NADPH Oxidase 4 Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS4380143
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman. Others not known
TargetNOX4/NADPH Oxidase 4
IsotypeIgG2b kappa
Molecular Weight70kDa
CloneNOX4/1245
HostMouse
ImmunogenThe superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells
NCBI Full Gene NameNADPH oxidase 4
NCBI Gene AliasesKOX, RENOX, KOX-1
ClonalityMonoclonal